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Publications
Book Chapters
 Mathematical concepts in pharmacokinetics and pharmacodynamics
with application to tumor growth
to appear in "Nonautonomous dynamics in the life
sciences" (Springer)
(with J. Schropp)
Peer-Reviewed Journals
2014
Anticancer combination effects of gemcitabine and Et-743 in-vitro
(with X. Miao and WJ. Jusko )
Modeling of delays in PKPD: classical approaches and a tutorial for delay
differential equations
(with W. Krzyzanski, JJ. Perez-Ruixo and J. Schropp)
Journal of Pharmacokinetics and Pharmacodynamics. 2014;41(4):291-318
2013 and older
Solution and implementation of distributed
lifespan models
(with J. Schropp)
Journal of Pharmacokinetics and Pharmacodynamics. 2013;40(6):639-650
General relationship between transit compartments and lifespan models
Journal of Pharmacokinetics and Pharmacodynamics. 2012;39(4):343-355
(with J. Schropp)
Multi-response model for rheumatoid arthritis based on delay differential
equations in collagen-induced arthritic mice treated with an anti-GM-CSF
antibody
Journal of Pharmacokinetics and Pharmacodynamics. 2012;39(1):55-65
(with T. Wagner, C. Plater-Zyberk, G. Lahu and J. Schropp)
Modeling of tumor growth and anticancer effects of
combination therapy
Journal of Pharmacokinetics and Pharmacodynamics. 2009;36(2):179-197
(with A. Walz, G. Lahu and J. Schropp)
(=under construction,
 =submitted,
=published/accepted)
Talks
PAGE 2012: Modeling of delayed phenomena in PKPD by delay differential equations of lifespan type
PhD Thesis
Modeling of Pharmacokinetics and Pharmacodynamics with Application to Cancer and Arthritis
Universität Konstanz, 2012
Poster
PAGE 2014:
Solving Semi-Delay Differential Equations in NONMEM
AAPS 2013: Mechanism-Based Drug Interaction Model of Gemcitabine and
Ecteinascidin (Et-743) in Pancreatic Cancer Cells
PAGE 2013:
Solution and implementation of distributed lifespan models
PAGE 2011:
A multi-response model for rheumatoid arthritis based on delay differential
equations in collagen induced arthritis mice treated with an anti-GM-CSF
antibody
Life Sciences - Bilder des Lebens 2009:
Mathematik im Medikament / Mathematische Modellierung in der
Medikamentenentwicklung
Articles for Magazines
2008
Uni'kon: Mathematik im
Medikament
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